Zhihua Wang
Postdoctoral Fellow
I obtained my PhD degree at the Institute for Cardiovascular Prevention (IPEK) at the Ludwig Maximilans University (LMU) in Munich. I am currently a postdoctoral fellow at the first affiliated hospital of Sun Yat-sen University. My research focuses on the mechanisms that regulate immune tolerance in the development of atherosclerosis. In my recently published paper, I revealed the multilayered breakdown of peripheral T-cell immune checkpoints in advanced atherosclerosis.
PUNLICATIONS
7. Zhihua Wang, Ting Sun, Yixin Zhang, Yutao Li, Chuankai Zhang, Xinwen Dou, Xinyi Deng, Zhipeng Li, Jingpu Zhu, Mingyang Hong, Yi Ran, Shu Wang, Liping Li, Junjie Zheng, Cong Wen, Xi Zhang, Shu Lu, Sagar, Sarajo K. Mohanta,
Andreas J.R. Habenicht & Changjun Yin.Fitness Training for γδ T cells in mouse and human atherosclerosis takes place in plaques and artery tertiary lymphoid organs,Genome Medicine, 24 February 2026.
doi: 10.1186/s13073-026-01613-1
6. Zhihua Wang, Xi Zhang, Shu Lu, Chuankai Zhang, Zhe Ma, Rui Su, Yuanfang Li, Ting Sun, Yutao Li, Mingyang Hong, Xinyi Deng, Rafiee Mohammad, Michael Hristov, Sabine Steffens, Donato Santovito, Klaus Dornmair, Klaus Ley, Christian Webe, Sarajo Mohanta, Andreas Habenicht, Changjun Yin. Nature Cardiovascular Research. 2, 290–306 (2023).
doi: 10.1038/s44161-023-00218-w
5. Livia Habenicht, Zhihua Wang, Xi Zhang, Yuanfang Li, Carolin Mogler, Julia Slotta Huspenina, Roland M. Schmid, Christian Weber, Sarajo Mohanta, Zhe Ma, Changjun Yin. The C1q-ApoE Complex: A New Hallmark Pathology of Virus Hepatitis and Nonalcoholic Fatty Liver Disease. Front Immunol. 2022; 13: 970938. doi: 10.3389/fimmu.2022.970938
4. Zhihua Wang, Xi Zhang, Chuankai Zhang, Yutao Li, Shu Lu, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Combined Single-Cell RNA and Single-Cell α/β T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis. Methods Mol Biol. 2022;2419:727-746. (book chapter).doi: 10.1007/978-1-0716-1924-7_44
3. Xi Zhang, Zhihua Wang, Chuankai Zhang, Yutao Li, Shu Lu, Sabine Steffens, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Laser Capture Microdissection-Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research. Methods Mol Biol. 2022;2419:715-726. (book chapter). doi: 10.1007/978-1-0716-1924-7_43
2. Zhihua Wang, Sheng Yuan, Yanbing Li, Zhe Zhang, Wei Xiao, Dan Tang, Kaihe Ye, Zhijun Liu, Congcong Wang, Yixiong Zheng, Hong Nie, Heru Chen. Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications. Biochem Pharmacol. 2018 Apr;150:54-63.doi: 10.1016/j.bcp.2018.01.034
1.Dan Tang, YingBin Shen, ZhiHua Wang, Bao He, YouHua Xu, Hong Nie, Quan Zhu. Rapid Analysis and Guided Isolation of Astragalus Isoflavonoids by UHPLC-DAD-MSn and Their Cellular Antioxidant Defense on High-Glucose-Induced Mesangial Cell Dysfunction. J Agric Food Chem. 2018 Feb.
Yuexiu District 510080 Guangzhou,China
Zhihua Wang
Postdoctoral Fellow
I obtained my PhD degree at the Institute for Cardiovascular Prevention (IPEK) at the Ludwig Maximilans University (LMU) in Munich. I am currently a postdoctoral fellow at the first affiliated hospital of Sun Yat-sen University. My research focuses on the mechanisms that regulate immune tolerance in the development of atherosclerosis. In my recently published paper, I revealed the multilayered breakdown of peripheral T-cell immune checkpoints in advanced atherosclerosis.
7. Zhihua Wang, Ting Sun, Yixin Zhang, Yutao Li, Chuankai Zhang, Xinwen Dou, Xinyi Deng, Zhipeng Li, Jingpu Zhu, Mingyang Hong, Yi Ran, Shu Wang, Liping Li, Junjie Zheng, Cong Wen, Xi Zhang, Shu Lu, Sagar, Sarajo K. Mohanta,
Andreas J.R. Habenicht & Changjun Yin.Fitness Training for γδ T cells in mouse and human atherosclerosis takes place in plaques and artery tertiary lymphoid organs,Genome Medicine, 24 February 2026.
doi: 10.1186/s13073-026-01613-1
6. Zhihua Wang, Xi Zhang, Shu Lu, Chuankai Zhang, Zhe Ma, Rui Su, Yuanfang Li, Ting Sun, Yutao Li, Mingyang Hong, Xinyi Deng, Rafiee Mohammad, Michael Hristov, Sabine Steffens, Donato Santovito, Klaus Dornmair, Klaus Ley, Christian Webe, Sarajo Mohanta, Andreas Habenicht, Changjun Yin. Nature Cardiovascular Research. 2, 290–306 (2023).
doi: 10.1038/s44161-023-00218-w
5. Livia Habenicht, Zhihua Wang, Xi Zhang, Yuanfang Li, Carolin Mogler, Julia Slotta Huspenina, Roland M. Schmid, Christian Weber, Sarajo Mohanta, Zhe Ma, Changjun Yin. The C1q-ApoE Complex: A New Hallmark Pathology of Virus Hepatitis and Nonalcoholic Fatty Liver Disease. Front Immunol. 2022; 13: 970938. doi: 10.3389/fimmu.2022.970938
4. Zhihua Wang, Xi Zhang, Chuankai Zhang, Yutao Li, Shu Lu, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Combined Single-Cell RNA and Single-Cell α/β T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis. Methods Mol Biol. 2022;2419:727-746. (book chapter).doi: 10.1007/978-1-0716-1924-7_44
3. Xi Zhang, Zhihua Wang, Chuankai Zhang, Yutao Li, Shu Lu, Sabine Steffens, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Laser Capture Microdissection-Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research. Methods Mol Biol. 2022;2419:715-726. (book chapter). doi: 10.1007/978-1-0716-1924-7_43
2. Zhihua Wang, Sheng Yuan, Yanbing Li, Zhe Zhang, Wei Xiao, Dan Tang, Kaihe Ye, Zhijun Liu, Congcong Wang, Yixiong Zheng, Hong Nie, Heru Chen. Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications. Biochem Pharmacol. 2018 Apr;150:54-63.doi: 10.1016/j.bcp.2018.01.034
1. Dan Tang, YingBin Shen, ZhiHua Wang, Bao He, YouHua Xu, Hong Nie, Quan Zhu. Rapid Analysis and Guided Isolation of Astragalus Isoflavonoids by UHPLC-DAD-MSn and Their Cellular Antioxidant Defense on High-Glucose-Induced Mesangial Cell Dysfunction. J Agric Food Chem. 2018 Feb.doi: 10.1021/acs.jafc.7b02949
PUNLICATIONS