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Zhihua Wang

Postdoctoral Fellow

I obtained my PhD degree at the Institute for Cardiovascular Prevention (IPEK) at the Ludwig Maximilans University (LMU) in Munich. I am currently a postdoctoral fellow at the first affiliated hospital of Sun Yat-sen University. My research focuses on the mechanisms that regulate immune tolerance in the development of atherosclerosis. In my recently published paper, I revealed the multilayered breakdown of peripheral T-cell immune checkpoints in advanced atherosclerosis.

6.    Zhihua Wang, Xi Zhang, Shu Lu, Chuankai Zhang, Zhe Ma, Rui Su, Yuanfang Li, Ting Sun, Yutao Li, Mingyang Hong, Xinyi Deng, Rafiee Mohammad, Michael Hristov, Sabine Steffens, Donato Santovito, Klaus Dornmair, Klaus Ley, Christian Webe, Sarajo Mohanta, Andreas Habenicht, Changjun Yin. Nature Cardiovascular Research. 2, 290–306 (2023). 

doi: 10.1038/s44161-023-00218-w


5.    Livia Habenicht, Zhihua Wang, Xi Zhang, Yuanfang Li, Carolin Mogler, Julia Slotta Huspenina, Roland M. Schmid, Christian Weber, Sarajo Mohanta, Zhe Ma, Changjun Yin. The C1q-ApoE Complex: A New Hallmark Pathology of Virus Hepatitis and Nonalcoholic Fatty Liver Disease. Front Immunol. 2022; 13: 970938. ​doi: 10.3389/fimmu.2022.970938


4.    Zhihua Wang, Xi Zhang, Chuankai Zhang, Yutao Li, Shu Lu, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Combined Single-Cell RNA and Single-Cell α/β T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis. Methods Mol Biol. 2022;2419:727-746. (book chapter).doi: 10.1007/978-1-0716-1924-7_44


3.    Xi Zhang, Zhihua Wang, Chuankai Zhang, Yutao Li, Shu Lu, Sabine Steffens, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Laser Capture Microdissection-Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research. Methods Mol Biol. 2022;2419:715-726. (book chapter). doi: 10.1007/978-1-0716-1924-7_43


2.    Zhihua Wang, Sheng Yuan, Yanbing Li, Zhe Zhang, Wei Xiao, Dan Tang, Kaihe Ye, Zhijun Liu, Congcong Wang, Yixiong Zheng, Hong Nie, Heru Chen. Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications. Biochem Pharmacol. 2018 Apr;150:54-63.doi: 10.1016/j.bcp.2018.01.034


1.    Dan Tang, YingBin Shen, ZhiHua Wang, Bao He, YouHua Xu, Hong Nie, Quan Zhu. Rapid Analysis and Guided Isolation of Astragalus Isoflavonoids by UHPLC-DAD-MSn and Their Cellular Antioxidant Defense on High-Glucose-Induced Mesangial Cell Dysfunction. J Agric Food Chem. 2018 Feb.doi: 10.1021/acs.jafc.7b02949

PUNLICATIONS

微信图片_20241025101648.jpg

Zhihua Wang

Postdoctoral Fellow

I obtained my PhD degree at the Institute for Cardiovascular Prevention (IPEK) at the Ludwig Maximilans University (LMU) in Munich. I am currently a postdoctoral fellow at the first affiliated hospital of Sun Yat-sen University. My research focuses on the mechanisms that regulate immune tolerance in the development of atherosclerosis. In my recently published paper, I revealed the multilayered breakdown of peripheral T-cell immune checkpoints in advanced atherosclerosis.

PUNLICATIONS

6.    Zhihua Wang, Xi Zhang, Shu Lu, Chuankai Zhang, Zhe Ma, Rui Su, Yuanfang Li, Ting Sun, Yutao Li, Mingyang Hong, Xinyi Deng, Rafiee Mohammad, Michael Hristov, Sabine Steffens, Donato Santovito, Klaus Dornmair, Klaus Ley, Christian Webe, Sarajo Mohanta, Andreas Habenicht, Changjun Yin. Nature Cardiovascular Research. 2, 290–306 (2023). 

doi: 10.1038/s44161-023-00218-w


5.    Livia Habenicht, Zhihua Wang, Xi Zhang, Yuanfang Li, Carolin Mogler, Julia Slotta Huspenina, Roland M. Schmid, Christian Weber, Sarajo Mohanta, Zhe Ma, Changjun Yin. The C1q-ApoE Complex: A New Hallmark Pathology of Virus Hepatitis and Nonalcoholic Fatty Liver Disease. Front Immunol. 2022; 13: 970938. ​doi: 10.3389/fimmu.2022.970938


4.    Zhihua Wang, Xi Zhang, Chuankai Zhang, Yutao Li, Shu Lu, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Combined Single-Cell RNA and Single-Cell α/β T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis. Methods Mol Biol. 2022;2419:727-746. (book chapter).doi: 10.1007/978-1-0716-1924-7_44


3.    Xi Zhang, Zhihua Wang, Chuankai Zhang, Yutao Li, Shu Lu, Sabine Steffens, Sarajo Mohanta, Christian Weber, Andreas Habenicht, Changjun Yin. Laser Capture Microdissection-Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research. Methods Mol Biol. 2022;2419:715-726. (book chapter). doi: 10.1007/978-1-0716-1924-7_43


2.    Zhihua Wang, Sheng Yuan, Yanbing Li, Zhe Zhang, Wei Xiao, Dan Tang, Kaihe Ye, Zhijun Liu, Congcong Wang, Yixiong Zheng, Hong Nie, Heru Chen. Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications. Biochem Pharmacol. 2018 Apr;150:54-63.doi: 10.1016/j.bcp.2018.01.034

1.Dan Tang, YingBin Shen, ZhiHua Wang, Bao He, YouHua Xu, Hong Nie, Quan Zhu. Rapid Analysis and Guided Isolation of Astragalus Isoflavonoids by UHPLC-DAD-MSn and Their Cellular Antioxidant Defense on High-Glucose-Induced Mesangial Cell Dysfunction. J Agric Food Chem. 2018 Feb.

doi: 10.1021/acs.jafc.7b02949

Yuexiu District 510080 Guangzhou,China

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